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3 Alternatives to Sex Drugs

November-December 2003




Viagra may be a wonder drug, but for some men, getting an erection isn't as easy as swallowing a pill. Nerve damage from injury, blood vessel disease, surgery, and even advanced diabetes can make you an inappropriate candidate for oral medications. But don't despair: Several alternatives can work for you. Among the most popular:

Intracavernous injection (ICI)
An ultrafine needle is used to deliver an erection-producing drug into your penis (and guess what, Romeo: you do the injection yourself). Only alprostadil (Caverject, Edex) is currently FDA-approved for penile injection. It works as a vasodilator, expanding blood vessels and enhancing smooth muscle relaxation so blood can rush to your penis. Urologists may also ask compounding pharmacists (pharmacists who mix customized, specialized medications) to prepare an off-label injectable generically known as Trimix. It combines alprostadil with other vasodilators, such as phentolamine and papaverine. Studies show that injections work in up to 88 percent of cases, and because the drug is localized, there are no major side effects. Yet despite its success, most patients don't stick with the therapy, typically because of pain from the injections and an aversion to any treatment involving the words "penis" and "needle." But ICI has its fervent supporters. "For the right guy," says Larry Lipshultz, M.D., professor of urology at Baylor College of Medicine in Houston, "it's easy to learn, easy to do, and produces good results." The cost is about $20 per injection.

Vacuum pumps
High-tech gadgets that operate on low-tech principles, vacuum pumps typically consist of hollow tubes that are placed over the penis, then activated to form a vacuum that sucks blood into the necessary vessels. Once Mr. Happy is engorged, a constriction ring is fitted at the base of the penis to keep that blood where it belongs. Pumps may score low on the discretion scale, but about 75 percent of their users report success. "They're cost-effective, reliable, and easy to use once you learn how," says Troy Burns, M.D., medical director of ProPartnersMD, a medical practice for men in Overland Park, Kansas. Many pumps are approved by the FDA for sale over the counter; prices range from $100 to $450.

Surgical implants
With this technique, surgeons implant a prosthesis in the penis—either a one-piece "malleable" unit that stays rigid (you bend it up to achieve an erection) or an inflatable device (two elongated chambers are placed inside the penis; you press an attached bulb hidden in the scrotum to get erect). The procedure is pricey—$10,000 and up, though it's often covered by insurance—and it's clearly one of the most invasive forms of treatment. But when all else fails, it's worth considering. "For a subset of men, prosthesis actually has the highest rate of satisfaction—higher than injections and oral drugs," says Francois Eid, M.D., clinical associate professor of urology at Weill Medical College of Cornell University. A recent study in The Journal of Urology found that 30 out of 32 patients who received implants were satisfied with the results 20 months later.

To find an ED expert, contact the American Urological Association online or toll free at 866-746-4282.