November 20, 2009



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Feed Your Head

By Kelly Griffin, September 2005

Add these healthy brain foods to your diet for a little peace of mind




Read All Articles in This Special Report

Inside Jim's Brain: How Scientists Are Untangling the Mysteries of Alzheimer's

What It Feels Like: A Personal Account of Living With Alzheimer's

He's Still in There: A Daughter's Perspective

Stay Sharp Longer: Nine Simple Things You Can Do

Finding Help: New Choices for People With Early-Stage Alzheimer's

Great Pretenders: Common Ailments and Drugs Known to Monkey With Memory

Back to the first article in this Special Report: You’re Wiser Now

For an incurable disease like Alzheimer's, an ounce of prevention is worth much more than a pound of cure—it's priceless. Fortunately, a healthy dose of preventive medicine is as near as your local farmers' market. Fresh fruits and vegetables are proven winners in the fight to stave off dementia, and some research even suggests that these powerful plant foods may turn back the cognitive clock.

"Fruits and vegetables are like mutual funds," says University of Kentucky professor of neurology David Snowdon, Ph.D. "They're a big pot of literally thousands of compounds that offer protection against a variety of diseases, including Alzheimer's disease." Snowdon, who has devoted his career to identifying factors that reduce the risk of Alzheimer's and other brain diseases, ranks fruit and vegetable intake number one on his hit list for middle-aged and older adults.

Though there's hardly a poor choice among them, here are some of the best of the bunch when it comes to feeding your brain:

Cruciferous vegetables. Harvard researchers recently reported that women in the Nurses' Health Study who ate the most broccoli, cauliflower, and other cruciferous vegetables performed better on memory tests than women the same age who ate the least. The difference in memory performance was the equivalent of being about two years younger. Cruciferous vegetables also seemed to put the brakes on age-related declines in memory and thinking, turning back the cognitive clock by about a year and a half.

Green leafy vegetables. Spinach and other leafy greens are among the richest sources of folate. This B vitamin appears to play a major role in preventing stroke, which accounts for 25 percent of dementia cases. Folate may also play a role in reducing the risk of Alzheimer's disease by helping the body break down homocysteine, an amino acid that is toxic to nerve cells.

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Blueberries. In tests of antioxidant power, blueberries take the blue ribbon, beating out about 50 other fresh fruits and vegetables. They also combat inflammation. In the fight against Alzheimer's disease, that one-two punch is hard to beat, according to neuroscientist James Joseph, Ph.D., of the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University. "Inflammation and oxidative stress are the evil Gemini twins of aging," says Joseph. "Where you see one, you see the other." Joseph calls blueberries the Dr. Phil of nerve cells because they get aging brain cells talking to each other.

Healthy fats. Your brain is about 60 percent fat, so when it comes to feeding your head, go a little nuts. Yes, nuts are high in fat, but it's the right kind of fat—cholesterol-lowering, artery-protecting, inflammation-fighting fat. Other smart choices for a healthy brain include monounsaturated oils like olive and canola, and fatty fish such as salmon, mackerel, and tuna. Population studies have shown that people whose diets are high in these unsaturated, unhydrogenated fats may have a reduced risk of Alzheimer's disease, while those whose diets are higher in saturated fats (from meat and dairy) and trans fats (from margarine and hydrogenated oils) have an increased risk.

Alcohol and juice. Moderate alcohol consumption is known to help the heart, but new research suggests it also benefits the brain, most likely by boosting blood flow and reducing the risk of tiny strokes. Moderate drinkers (women who average one half to one drink and men who consume one to two drinks per day) perform better on cognitive tests and show less decline in cognitive function over time than nondrinkers. Fruit and vegetable juice may be just as protective. At the first International Conference on the Prevention of Dementia this June, researchers reported that older adults who drank at least three glasses of juice a week had a 75 percent lower risk of Alzheimer's disease compared to those who drank juice less than once a week.

Protection in a pill? While it may seem simpler to swallow a handful of vitamins, minerals, and herbs, most experts caution against supplementing with the nutrient du jour. "All of these goodies have a curve," says Joseph, "and you have to stay on the right side of the curve." For example, at high doses, antioxidants like vitamins C and E can become pro-oxidants. There's another reason for caution—even though some studies have linked low intakes or low blood levels of nutrients to an increased risk of dementia, there's scant evidence that stocking up on nutritional supplements reduces risk.

Older adults may benefit from supplements of the homocysteine-lowering B vitamins folic acid and B12, since deficiencies of these nutrients become more common with age. And if fish isn't your dish, an omega-3 fatty acid supplement is probably a good idea. But if you want to keep your wits about you, your best bet is to diversify your portfolio by eating a wide range of colorful plant foods, choosing healthy fats, and enjoying an occasional glass of wine. Bon appétit!